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Vitexin 90 - Zenius Labs™

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4.65 (51)
4.8/5

Anxiety control medication side effects are well known [70]. Medicinal plants derived natural compounds are comparably effective [30, 66], except the usual risk of serious side-effects [39]. Furthermore being neuroprotective [35] and improving cognitive function [60].

Two compounds. One force

Vitexin is a natural flavonoid extracted from P. Incarnata flower. It binds to (benzodiazepine) GABAa receptors therefore calming Central Nervous System. Documented trials suggest it is as effective as a conventional medicine in eliminating anxiety symptoms just without the side effects.
Raw Capsule

Natural polysaccharides extracted from Hericium Erinaceus medicinal mushroom has clinically shown the ability to stimulate nerve regeneration, promote neuronal survival, improve cognitive functions, ameliorate anxiety, improve mood and sleep.

Not opinions, just facts

Research shows [30, 31, 32] that natural compound Vitexin can reduce anxiety as well as conventional chemical medicine.

It binds to the same benzodiazepine receptors in the brain as anti-anxiety or anti-depressant medication [33, 34, 35].

Just without the usual risk of serious side effects common to prescription anti-anxiety medication [36, 37, 38, 39, 40, 41] (memory problems, slow movements, addiction).

Conclusively, flavonoid extracts such as Vitexin are most suitable for anxiety, stress and depression [43, 44, 45, 46, 47, 48, 49, 50].

Vitexin also improves learning and memory, and helps with neurological disorders. Promotes neuron survival and reduces inflammation [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21].

The brain and neurons are particularly sensitive to oxidative stress. Vitexin protects the brain from destructive oxidative damage and brain injury [22, 23, 24, 25, 26].

Sleep disorders contribute to neurodegenerative diseases. Vitexin improves sleep and memory further protecting the brain [27, 28, 29].

Vitexin also has many other beneficial health effects:
Anti-inflammation [1, 2, 4]
Cardioprotective effect [3, 4]
Cancer and autophagy [5]
Antibacterial activity [6, 7]
Bone protection [8]

Substantial evidence has proven the safety and tolerability profiles of these compounds in vivo and in vitro [4].

Natural H. Erinaceus medicinal mushroom extracts have clinically shown the ability to:
Stimulate Neurite Outgrowth (nerve regeneration) [51, 54, 55, 56, 57, 58]
Promote neuronal survival [52, 53, 54, 69]
Improve cognitive functions [59, 60, 63, 64]
Ameliorate anxiety [51, 61, 66]
Improve depression, mood [62, 65, 67, 68] and sleep [61, 62].

Vitexin 90 Customer Reviews

4.65 (51)
4.7/5
Robert Y.
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Strong but natural extracts, no side effects. It is not only effective in keeping me calm without making me feel tired, I feel more capable, relaxed, smart and focused. I’m using everyday longterm. Hericium extract alone makes the brain repair and function more efficiently, this is not some symptom masking this is evolution. Thank you.
Darius
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Great product! It really helps with reducing anxiety, highlyrecomended
Natalie D.
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I recommend this product to anyone with anxiety or even stress
Supplements for Anxiety

Get started with Vitexin 90 Today

Get your mind back on track. Active compounds are clinically validated to impact your nerve regeneration and neurotransmitter balance.
Supplements for Anxiety

Get Started with Vitexin 90 Today

Get your mind back on track. Active compounds are clinically validated to impact your neurotransmitter balance and nerve regeneration.

Still Have Questions?

SKU ZN32618MB
Tags Anxiety control

Sources

1. Absorption, metabolism, and bioactivity of vitexin: recent advances in understanding the efficacy of an important nutraceutical.
[Pubmed]

2. Vitexin reduces neutrophil migration to inflammatory focus by down-regulating pro-inflammatory mediators via inhibition of p38, ERK1/2 and JNK pathway.
[ScienceDirect]

3. Vitexin exerts cardioprotective effect on chronic myocardial ischemia/reperfusion injury in rats via inhibiting myocardial apoptosis and lipid peroxidation.
[Europe PMC]

4. Multitargeted Effects of Vitexin and Isovitexin on Diabetes Mellitus and Its Complications.
[Pubmed]

5. Molecular targets of vitexin and isovitexin in cancer therapy: a critical review.
[Pubmed]

6. Antibacterial activity of pure flavonoids isolated from mosses.
[Pubmed]

7. Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin.
[Pubmed]

8. Vitexin suppresses RANKL-induced osteoclastogenesis and prevents lipopolysaccharide (LPS)-induced osteolysis.
[Wiley]

9. Vitexin as an active ingredient in passion flower with potential as an agent for nicotine cessation: vitexin antagonism of the expression of nicotine locomotor sensitization in rats.
[Tandfonline]

10. Vitexin alleviates lipopolysaccharide‑induced islet cell injury by inhibiting HMGB1 release.
[Spandidos publications]

11. Neuroprotective effects of vitexin against isoflurane-induced neurotoxicity by targeting the TRPV1 and NR2B signaling pathways.
[Spandidos publications]

12. Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway.
[ScienceDirect]

13. Improvement in neurogenesis and memory function by administration of Passiflora incarnata L. extract applied to sleep disorder in rodent models.
[ScienceDirect]

14. Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1.
[BioMedCentral]

15. Phytochemical distribution in hull and cotyledon of adzuki bean (Vigna angularis L.) and mung bean (Vigna radiate L.), and their contribution to antioxidant, anti-inflammatory and anti-diabetic activities.
[ScienceDirect]

16. Protective effect of vitexin reduces sevoflurane-induced neuronal apoptosis through HIF-1α, VEGF and p38 MAPK signaling pathway in vitro and in newborn rats.
[Spandidos publications]

17. Improvement of spatial learning and memory, cortical gyrification patterns and brain oxidative stress markers in diabetic rats treated with Ficus deltoidea leaf extract and vitexin.
[ScienceDirect]

18. Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexin.
[BioMedCentral]

19. Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain.
[Oncotarget]

20. Vitexin reduces hypoxia–ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model.
[ScienceDirect]

21. Vitexin inhibits inflammatory pain in mice by targeting TRPV1, oxidative stress, and cytokines.
[Pubmed]

22. Vitexin protects against ischemia/reperfusion-induced brain endothelial permeability.
[ScienceDirect]

23. Grewia tiliaefolia and its active compound vitexin regulate the expression of glutamate transporters and protect Neuro-2a cells from glutamate toxicity.
[ScienceDirect]

24. Vitexin inhibits Aβ25-35 induced toxicity in Neuro-2a cells by augmenting Nrf-2/HO-1 dependent antioxidant pathway and regulating lipid homeostasis by the activation of LXR-α.
[ScienceDirect]

25. Vitexin reduces hypoxia–ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model.
[ScienceDirect]

26. Vitexin protects brain against ischemia/reperfusion injury via modulating mitogen-activated protein kinase and apoptosis signaling in mice.
[ScienceDirect]

27. Improvement in neurogenesis and memory function by administration of Passiflora incarnata L. extract applied to sleep disorder in rodent models.
[ScienceDirect]

28. Effects of vitexin on scopolamine-induced memory impairment in rats.
[Pubmed]

29. Improvement in neurogenesis and memory function by administration of Passiflora incarnata L. extract applied to sleep disorder in rodent models.
[Pubmed]

30. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam.
[Pubmed]

31. Assessment of Passiflora incarnata L for conscious sedation of patients during the extraction of mandibular third molars: a randomized, split-mouth, double-blind, crossover study.
[Pubmed]

32. Passiflora incarnata in Neuropsychiatric Disorders—A Systematic Review.
[Pubmed]

33. Flavones-bound in benzodiazepine site on GABA A receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin.
[Pubmed]

34. Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system.
[Pubmed]

35. Neuroprotective effects of vitexin, a flavonoid, on pentylenetetrazole-induced seizure in rats.
[Pubmed]

36. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.
[Pubmed]

37. Effects of Passion Flower Extract, as an Add-On Treatment to Sertraline, on Reaction Time in Patients ‎with Generalized Anxiety Disorder: A Double-Blind Placebo-Controlled Study.
[Pubmed]

38. Vitexin improves neuron apoptosis and memory impairment induced by isoflurane via regulation of miR-409 expression.
[Pubmed]

39. Review of the effects of vitexin in oxidative stress‐related diseases.
[Pubmed]

40. Passionflower in the treatment of opiates withdrawal: a double-blind randomized controlled trial.
[Pubmed]

41. Drug/substance reversal effects of a novel tri-substituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn.–a brief perspective.
[Pubmed]

43. Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms.
[Pubmed]

44. Dual protective effect of Passiflora incarnata in epilepsy and associated post-ictal depression.
[Pubmed]

45. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.
[Pubmed]

46. A combination of plant extracts in the treatment of outpatients with adjustment disorder with anxious mood: controlled study versus placebo.
[Pubmed]

47. Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors.
[Pubmed]

47. Effects of Passion Flower Extract, as an Add-On Treatment to Sertraline, on Reaction Time in Patients ‎with Generalized Anxiety Disorder: A Double-Blind Placebo-Controlled Study.
[Pubmed]

49. Vitexin Possesses Anticonvulsant and Anxiolytic-Like Effects in Murine Animal Models.
[Pubmed]

50. Vitexin ameliorates chronic stress plub high fat diet-induced nonalcoholic fatty liver disease by inhibiting inflammation.
[Pubmed]

51. Neurotrophic properties of the Lion’s mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.
[Pubmed]

52. The influence of Hericium erinaceus extract on myelination process in vitro.
[Pubmed]

53. Neuroregenerative potential of lion’s mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (higher Basidiomycetes), in the treatment of peripheral nerve injury (review).
[Pubmed]

54. Chemical Constituents from Hericium erinaceus Promote Neuronal Survival and Potentiate Neurite Outgrowth via the TrkA/Erk1/2 Pathway.
[Pubmed]

55. Neurite outgrowth stimulatory effects of myco synthesized AuNPs from Hericium erinaceus (Bull.: Fr.) Pers. on pheochromocytoma (PC-12) cells.
[Pubmed]

56. Hericium erinaceus (Bull.: Fr) Pers. cultivated under tropical conditions: isolation of hericenones and demonstration of NGF-mediated neurite outgrowth in PC12 cells via MEK/ERK and PI3K-Akt signaling pathways.
[Pubmed]

57. Chemical constituents from Hericium erinaceus and their ability to stimulate NGF-mediated neurite outgrowth on PC12 cells.
[Pubmed]

58. Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells.
[Pubmed]

59. Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice.
[Pubmed]

60. Improvement of cognitive functions by oral intake of Hericium erinaceus.
[Pubmed]

61. Hericium erinaceus mycelium ameliorate anxiety induced by continuous sleep disturbance in vivo.
[Pubmed]

62. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?
[Pubmed]

63. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.
[Pubmed]

64. Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice.
[Pubmed]

65. Therapeutic Potential of Hericium erinaceus for Depressive Disorder.
[Pubmed]

66. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake.
[Pubmed]

67. Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression.
[Pubmed]

68. Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus.
[Pubmed]

69. The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model.
[Pubmed]

70. Systematic review of the side effects of benzodiazepines.
[Pubmed]